基于模糊谱聚类的不确定蛋白质相互作用网络功能模块挖掘

针对谱聚类融合模糊C-means（FCM）聚类的蛋白质相互作用（PPI）网络功能模块挖掘方法准确率不高、执行效率较低和易受假阳性影响的问题，提出一种基于模糊谱聚类的不确定PPI网络功能模块挖掘（FSC-FM）方法。首先，构建一个不确定PPI网络模型，使用边聚集系数给每一条蛋白质交互作用赋予一个存在概率测度，克服假阳性对实验结果的影响；第二，利用基于边聚集系数流行距离（FEC）策略改进谱聚类中的相似度计算，解决谱聚类算法对尺度参数敏感的问题，进而利用谱聚类算法对不确定PPI网络数据进行预处理，降低数据的维数，提高聚类的准确率；第三，设计基于密度的概率中心选取策略（DPCS）解决模糊C-means算法对初始聚类中心和聚类数目敏感的问题，并对预处理后的PPI数据进行FCM聚类，提高聚类的执行效率以及灵敏度；最后，采用改进的边期望稠密度（EED）对挖掘出的蛋白质功能模块进行过滤。在酵母菌DIP数据集上运行各个算法可知，FSC-FM与基于不确定图模型的检测蛋白质复合物（DCU）算法相比，F-measure值提高了27.92%，执行效率提高了27.92%；与在动态蛋白质相互作用网络中识别复合物的方法（CDUN）、演化算法（EA）、医学基因或蛋白质预测算法（MGPPA）相比也有更高的F-measure值和执行效率。实验结果表明，在不确定PPI网络中，FSC-FM适合用于功能模块的挖掘。     

Novel CPG algorithm for tracking fast sudden changes based on tangent rule

ABSTRACT

This paper proposes a novel tracking method to deal with fast changes of solar irradiation and power limit change in order to increase tracking efficiency. This goal is achieved by estimating (i) next operating mode and (ii) next step point with the use of tangent rule in triangle. After every fast response to sudden changes, accurate response phase starts in order to track desired power in each operating mode by adaptive step size. Drift problem in defining next operating mode is eliminated in proposed method by estimating next operating mode, and settling time is decreased to about 25 percent of settling time of other methods by estimating next step point. Simulation and experimental results show the performance of proposed method.     

Extensive evaluation and classification of low-cost dust sensors in laboratory using a newly developed test method

An extensive evaluation of low-cost dust sensors was performed using an exponentially decaying particle concentration. A total of 264 sensors including 27 sensors with light-emitting diodes (LEDs) and 237 sensors with laser lighting sources were tested. Those tested sensors were classified into 4 groups based on the deviation from the reference data obtained by a reference instrument. The response linearities of all the tested samples for PM₁, PM_2.5, and PM₁₀ were in excellent agreement with the reference instrument, except a few samples. For the measurements of PM₁ and PM_2.5, the lighting source, that is, LED or laser, did not show any significant difference in overall sensor performance. However, LED-based sensors did not perform well for PM₁₀ measurements. The 32, 24, and 16% of all the tested sensors for PM₁, PM_2.5, and PM₁₀ measurement, respectively, are in the category of Class 1 (reference instrument reading ± 20%) requirement. The performance of the low-cost dust sensors for PM₁₀ measurement was relatively less satisfactory.     

提升机启动操作中制动油泵软性停转的分析与排除

同一个多功能集控器件长期使用后，其不同故障程度对应有不同故障现象，为了加快现场技术管理人员对提升机疑难故障的有效排除进度，着重分析了制动油泵停转的控制通道，根据提升机启动操作中制动油泵停转后的排查处理结果，圈定了故障范围为变频控制器件。制动油泵在提升机启动操作中停转的不确定性，查找故障时整机电控系统处于非故障状态，接近更换变频主控板D6时启动提升机操作中制动油泵软性停转次数有所增多、启动中无发生制动油泵停转的全程提升未见异常，上述因素使制动油泵软性停转成为疑难杂症。故障现象恶化为每次操作至制动手把推向松闸位置制动油泵均停转，用梯形图确定D6故障是症结所在。对D6的自身故障精确定位功能且在变频控制柜人机界面RJ2显示故障信息认识不足，导致故障长时存在。此副井提升机有关人员应做到:对故障反映到位、深刻了解器件性能特征、透析有关动作过程后方可采取针对性措施、确定故障元件、最终排除故障。可恢复性的轻故障发生后必须采取相应措施，避免故障扩大导致停机延误提升。将变频就绪与故障的实时信息显示于司控台面，弥补了技改缺陷。     

Liquid phase sintering and characterization of SiC ceramics

The present study focuses on the sintering of silicon carbide-based ceramics (SiC) by liquid phase sintering (LPS) followed by characterization of the produced ceramics. AlN/Re₂O₃ mixtures were used as additives in the LPS process. In the first step, the LPS-SiC materials were produced in a graphite resistance furnace in the form of discs at different temperatures. The conditions with the best results regarding real density and relative density were taken as reference for sintering in the form of prismatic bars. In the second step, these samples were evaluated regarding fracture toughness (K_IC), by the Single Edge V Notch Beam – SEVNB – method, and flexural strength. K_IC behavior was evaluated according to the depth and curvature radius of the notches. Reliable K_IC values were presented when the ceramic displayed a small curvature radius at the notch tip. When the radius was large, it did not maintain the square root singularity of the notch tip. Tests were carried out to determine K_IC values in atmospheric air and water. K_IC results were lower in water than air, with a decrease ranging between 2.56% and 11.26%. The observations indicated a direct grain size correlation between K_IC values and fracture strength of the SiC ceramics.     

基于随机模型的动车组制动模块稳健优化设计

针对目前产品优化设计中未考虑设计变量随机性和灵敏度指数对产品质量特性的影响及优化求解效率低等问题，提出一种综合考虑灵敏度指数与质量损失函数的稳健优化设计方法。通过假设设计变量的分布类型，得到设计变量的概率分布特征，将设计变量对产品质量特性的灵敏度指数与质量损失函数加权整合，并以此作为优化目标，以设计变量的容差作为约束条件，构建随机稳健优化模型。通过扩大种群数目、改进控制参数及增加惩罚因子的方法对遗传算法进行改进，结合改进的遗传算法对优化模型进行求解，得到优化模型的全局稳健最优解。以某动车组制动模块为例，采用给出的方法对其进行稳健优化设计，验证该方法的有效性与合理性。优化结果表明，该方法能够实现动车组制动模块的稳健优化设计，提高了制动模块的抗干扰能力。     

煤矿科室工作信息管理系统设计

为了提高了煤矿工作者的工作效率和矿井安全程度，设计了煤矿科室工作信息管理系统，分析了系统的关键技术，主要为J2EE技术和B/S和C/S的体系结构；根据现场调研，对系统需求进行了分析，然后设计了系统总体架构和系统功能模块。煤矿科室工作信息管理系统的应用，减少了人力资源的浪费，确保了信息的保存和查询的安全性。     

一种双边自行车停车装置的设计

针对共享单车停放困难影响交通秩序的现状,迫切需要研发自行车停车装置。设计了一种“摩天轮”式新型双边立式自行车停车装置,由机械执行机构和控制系统两大部分组成。前者通过大转矩步进电机和蜗轮蜗杆减速箱带动圆盘转动形成旋转执行机构,可提供6个自行车车位;后者利用32位闪存微控制器STM32系列单片机来处理停车装置运行过程中产生的数据,实现用户在存取自行车过程中6个车位顺畅地切换以及定位。该装置具有空间利用率高、存取简便快捷、美观防盗等特点,为解决共享单车的停放管理问题提供一种可参考的解决方案。     

5G光模块技术及方案对比

论述了5G光模块的技术和产业化发展现状,分析了4种波分复用技术应用于5G前传网络的优缺点,给出了后续5G光模块发展的策略建议.     

低温水等离子体活化和表面接枝DMAE聚氯乙烯中空纤维膜研究

采用低温水等离子体技术，在三通道聚氯乙烯(PVC)膜表面接枝了甲基丙烯氧基苄基二甲基氯化铵(DMAE)单体，增强了膜亲水和抗菌性能。通过红外分析，表明DMAE成功接枝到了PVC膜上，水通量提高两倍，PVC-ir-H₂O膜(通过水等离子体处理的膜)对牛血清蛋白(BSA)的吸附能力下降67%，对BSA溶液的通量从7.7提高至40 kg?m^-2?h^-1，并且对BSA的截留能力不变。通过静态及动态抗菌实验，接枝后的PVC膜（PVC-g-PMAE膜）抗菌率达到100%，膜组件运行中的抗菌率也达到82%以上。在保证细菌截留率100%的同时，其渗透通量提高三倍。该膜表面修饰工程技术能实现膜表面的均一化改性，且绿色环保、操作简便、成本低，改性膜在饮用水处理领域，尤其是家用净水器中展现了很好的应用前景。